Technical Lab - Scientist, LC-MS/MS Method Development

Apply advanced scientific expertise and methods to design, develop, and implement drugs of abuse mass spectrometry assays. Conduct development, feasibility, and validation studies applying advanced scientific principles to projects or products of strategic importance to the organization. Train and guide scientific personnel at various levels as needed and offer scientific design and statistical analysis to assigned projects.

• Plan research methodology and formulate experimental designs for medium to large-scale projects. Conduct experiments, record data, and identify issues and opportunities observed during the research process. Possess strong knowledge of scientific methods and establish logical research procedures. Proficient in statistical methods and Design of Experiments techniques. Understand the product development process and concepts of design for manufacturability.
• Oversee and validate the recording of experimental results in authorized company-owned laboratory notebooks for all staff members involved in medium to large-scale projects. Periodically review and co-sign notebooks to verify the accuracy of recorded results and intellectual property concepts.
• Promote innovation and original thinking in the execution of development tasks for medium to large-scale projects. Lead project staff towards new developments in technical expertise.
• Assist in preparing technical SOPs, assay validation reports, and other assay-related documentation for medium to large-scale projects. Lead project presentations or demonstrations to customers or management, demonstrating excellent oral and written communication skills. Interact with project team members, peers, other divisions, customers, and suppliers to resolve day-to-day issues and achieve results.
• Drive compliance with industry regulatory and quality standards for Assay Design Control processes.

• Ability to design and develop LC-MS/MS-based assays for the detection and quantification of target analytes in biological specimens (urine, oral fluid, hair).
• Experience optimizing assay parameters such as sample preparation, chromatography, and mass spectrometry conditions to achieve high sensitivity, specificity, and accuracy.
• Experience in a GMP or QSR environment preferred.
• Experience with relevant scientific computing applications.
• Analyze and interpret LC-MS/MS data to generate accurate and reliable results.
• Maintain and troubleshoot LC-MS/MS instrumentation and software with little assistance.
• Ability to lead a mass spectrometry-based project with minimal oversight. Technical competency required to manage laboratory systems.
• Ability to write, interpret, and critique technical specifications and related documentation with little assistance.

• Demonstrate advanced proficiency in the use of computers, including word processing, and spreadsheets.
• Demonstrated ability to drive continuous improvement and drive change.
• Highly effective written, verbal, and interpersonal skills.
• Proven ability to accomplish advanced technical tasks both independently and as a member of a research team.
• Ability to sit or stand for long periods of time.
• Work in a laboratory environment and adhere to safety requirements.

Minimum of a bachelor’s degree and minimum of 1-3 years of independent experience designing and developing LC-MS/MS. A proven track record of LC-MS/MS method development is required.

• Shift/TimeZone: Day Shift (roughly 8-5 with flexibility), M-F generally
• Sometimes OT or Weekend work may be needed/allowed.
• Hours Per Week: 40.00
• Days: Weekdays